What is Raspberry Ketone? Raspberry Ketone is the natural phenolic compound that creates the sweet smell of raspberries, and has been publicly heralded as a potent fat burner. How does Raspberry Ketone work? Raspberry Ketone has been shown to increase the expression and secretion of adiponectin. Adiponectin, a protein hormone, modulates a number of metabolic processes, such as glucose regulation and fatty acid catabolism. Prior adiponectin research has shown an inverse correlation between adiponectin levels and body fat percentage. Higher adiponectin = lower levels of body fat! Higher adiponectin has also been shown to control the metabolic derangements that may result in Type 2 Diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease and metabolic syndrome.